521) Neuroleptic Malignant Syndrome : A Five-Year Review
Author: Kasem Tantiphlachiva M.D.
Year: 1999
Source: Journal of The Psychiatric Association of Thailand, Vol. 44 No.3 July-September 1999, P 189-200.
Neuroleptic malignant syndrome (NMS) is the most serious and potentially fatal complication of neuroleptic pharmacotherapy. This is a retrospective study of cases at Somdet Chaopraya Hospital from 1994 to 1998. Twelve cases were diagnosed as developing NMS during the five-year period, revealing the incidence of 0.04%, which would have been higher if cases without laboratory investigations were included. Half of the patients were diagnosed as schizophrenia. Fever, sweating, muscle rigidity, leuco...